NFL Football
2025-10-05 - Tennessee Titans at Arizona Cardinals
A Sports Betting Pick by FirstDown
United States : NFL Week 5
Sunday 5th October 2025 - Scheduled 4:05pm
9:05pm (British Time)
Preview
Divisional losses really do hurt a lot more than a normal loss and a couple of those NFC West defeats have dropped the Arizona Cardinals (2-2) into the basement of that Division. They have had additional time to prepare for this Week 5 game and it is an important one, even in a non-Conference setting.
They are hosting a Tennessee Titans (0-4) team who have had their Number 1 Overall Pick Quarter Back voicing his frustrations this week at the way the season has unfolded to this point.
Cam Ward has to be given credit for wanting to win, but this is a very difficult situation to be dropped into and the Titans feel a long way from contending. Things can turn around in the NFL pretty quickly, especially as the Titans look like they could end up leading the way with the top Draft Pick in 2026 when a number of intriguing Quarter Backs could be coming into the League.
For now it is a struggle and the Titans have just had so many issues Offensively that it makes it tough to move the chains with any kind of consistency.
Everything begins on the Offensive Line and the Titans have simply not been able to run the ball with any authority, which shifts so much pressure onto the shoulders of a young Quarter Back. They are not expected to have a lot of ground success in this game and so it will be up to Cam Ward to find his Receivers and hope they can make some plays for him.
If the Offensive Line have struggled to help establish the run, they have been worse at giving Cam Ward the time to let routes develop down the field. Sacks have been racked up by opponents and that has contributed to a really poor passing game, which makes it tough to believe Tennessee can even expose this vulnerable Arizona Secondary.
Replacing James Connor is not going to be easy for the Arizona Cardinals, but Trey Benson can have a much stronger game than he did in the defeat to the Seattle Seahawks.
Where Seattle can play the run pretty well, this Titans Defensive Line have struggled to stop teams on the ground and Benson, along with Quarter Back Kyler Murray, should be able to keep the team in third and manageable spots on the field.
The Quarter Back was the leading rusher in the loss to Seattle, and his legs remain a big weapon, but the Cardinals will want to see a bit more consistency in the passing game. Kyler Murray should be able to target a couple of solid Receivers when in front of the chains considering the lack of pass rush pressure that the Titans have generated early this season, and with a Secondary that is allowing more and more yards in recent outings.
A connection with Marvin Harrison Jr is getting better all of the time and the Arizona Cardinals can use the extra prep time to make sure they are back over 0.500 by the end of Week 5. They can cover an awkward number with Murray having a 13-7 record against the spread when suffering back to back losses and the Cardinals may become the latest to get the better of Tennessee by at least 8 points.
Prediction
Lay the points with the big home favourite.
The Pick :
Arizona Cardinals 31-17 Tennessee Titans
